Clinical Trials Lyme Disease

Rank

Status

Study

1

Recruiting

Study on Early Lyme Neuroborreliosis

Condition:

Nervous System Lyme Borreliosis

Intervention:

Drug: ceftriaxone

2

Completed

Brain Imaging and Retreatment Study of Persistent Lyme Disease

Conditions:

Lyme Disease;   Lyme Neuroborreliosis

Intervention:

Drug: ceftriaxone

3

Not yet recruiting

Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis

Condition:

Suspected Early Lyme Neuroborreliosis

Interventions:

Drug: doxycycline;   Drug: ceftriaxone

4

Recruiting

Searching for Persistence of Infection in Lyme Disease

Conditions:

Lyme Disease;   Borrelia Burgdorferi

Interventions:

Procedure: Skin Biopsy;   Device: Xenodiagnosis;   Procedure: Blood Drawing

5

Terminated

Passive Prophylaxis of Lyme Disease Using Permethrin Treated Clothes

Condition:

Lyme Disease

Interventions:

Other: Permethrin;   Other: Placebo

6

Recruiting

Evaluation of Lyme Disease: Clinical, Microbiological and Immunological Characteristics

Conditions:

Chronic Disease;   Healthy;   Lyme Arthritis;   Lyme Disease;   Multiple Sclerosis

Intervention:

7

Recruiting

Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

Condition:

Lyme Disease

Intervention:

8

Unknown †

A School-Based Intervention to Reduce Lyme Disease

Condition:

Lyme Disease

Interventions:

Behavioral: Education;   Behavioral: Control (pre and post surveys)

9

Completed

Lyme Disease Prevention Program

Conditions:

Lyme Disease;   Tick-Borne Diseases

Intervention:

Behavioral: Education about disease prevention

10

Recruiting

Borrelia Species in Cutaneous Lyme Borreliosis

Condition:

Lyme Borreliosis

Intervention:

Other: Cutaneous biopsy

11

Recruiting

Persistent Lyme Empiric Antibiotic Study Europe

Conditions:

Lyme Disease;   Borrelia Infection

Interventions:

Drug: Doxycycline;   Drug: Clarithromycin and hydroxychloroquine;   Drug: Placebo

12

Completed

Study and Treatment of Post Lyme Disease (STOP-LD)

Condition:

Lyme Disease

Intervention:

Drug: Antibiotics

13

Completed

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seronegative Chronic Lyme Disease

Condition:

Lyme Disease

Interventions:

Drug: ceftriaxone;   Drug: doxycycline

14

Completed

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme Disease

Condition:

Lyme Disease

Interventions:

Drug: ceftriaxone;   Drug: doxycycline

15

Completed

Effect of Intravenous Ceftriaxone and Oral Doxycycline for Lyme Neuroborreliosis

Condition:

Lyme Neuroborreliosis

Interventions:

Drug: Ceftriaxone;   Drug: Doxycycline

16

Recruiting

Analysis of Lyme Disease Lesions

Conditions:

Erythema Migrans Lesions;   Erythema Migrans

Intervention:

17

Completed

The Phenomenon of "Chronic Lyme"; an Observational Study

Condition:

Chronic Lyme Borreliosis

Intervention:

18

Completed

Safety, Skin and Plasma Concentration of Azithromycin Dermal Formulation

Condition:

Lyme Disease

Intervention:

Drug: Application of SHB001

19

Recruiting

Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice

Conditions:

Erythema Migrans;   Erythema Chronicum Migrans;   Borreliosis;   Lyme Disease;   Early Lyme Disease

Interventions:

Drug: Doxycycline;   Drug: Phenoxymethylpenicillin;   Drug: Amoxicillin

20

Recruiting

Antibiotic Treatment of Multiple Erythema Migrans

Condition:

Multiple Erythema Migrans

Interventions:

Drug: ceftriaxone;   Drug: doxycycline;   Other: control subjects without a history of Lyme borreliosis;   Other: erythema migrans patients treated with doxycycline

21

Completed

Duration of Antibiotic Treatment of Erythema Migrans

Condition:

Erythema Chronicum Migrans

Interventions:

Drug: doxycycline;   Drug: placebo

22

Unknown †

Study of Anti-HIV Therapy Intensification

Condition:

HIV Infections

Interventions:

Drug: Lopinavir/Ritonavir;   Drug: Lamivudine/Zidovudine;   Drug: Tenofovir disoproxil fumarate;   Biological: Pneumococcal Vaccine, Polyvalent (23-valent);   Drug: Lamivudine;   Drug: Stavudine;   Drug: Zidovudine;   Drug: Didanosine;   Biological: Lyme Disease Vaccine Recombinant OspA;   Biological: Haemophilus B Conjugate Vaccine

23

Recruiting

Efficacy of 1072nm Infrared Stimulation on Executive Functioning in Dementia

Condition:

Dementia

Intervention:

Device: 1072nm infrared light stimulation

24

Recruiting

Human Anaplasmosis in Eastern France

Conditions:

Anaplasmosis;   Tick-borne Disease;   Ehrlichia

Intervention:

Procedure: Blood sampling

25

Completed

Post Exposure Treatment With Doxycycline for the Prevention of Relapsing Fever

Conditions:

Relapsing Fever, Tick-Borne;   Jarisch Herxheimer Reaction

Intervention:

Drug: doxycycline treatment

26

Unknown †

A Placebo-controlled Efficacy Study of IV Ceftriaxone for Refractory Psychosis

Conditions:

Psychosis;   Schizophrenia;   Schizoaffective Disorder

Interventions:

Drug: ceftriaxone;   Drug: Normal Saline

27

Recruiting

Investigation of Southern Tick-Associated Rash Illness (STARI)

Condition:

Southern Tick-Associated Rash Illness

Intervention:

28

Unknown †

Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study

Condition:

Idiopathic Pulmonary Fibrosis

Intervention:

Drug: minocycline

29

Completed

Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease

Condition:

Prophylaxis Herpes Simplex

Interventions:

Biological: Herpes simplex candidate vaccine- adjuvanted GSK208141;   Biological: Placebo injection

30

Completed

Safety Evaluation of Herpes Simplex Candidate Vaccine (gD2t) With Adjuvant in HSV Seropositive / Seronegative Subjects

Condition:

Prophylaxis for Herpes Simplex

Interventions:

Biological: Herpes simplex candidate vaccine- adjuvanted GSK 208141;   Biological: Placebo

31

Completed

The Study to Treat Superficial Femoral Artery Occlusions.

Condition:

Arterial Occlusive Diseases

Interventions:

Device: stent;   Device: angioplasty

32

Completed

A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic Children

Condition:

Autistic Disorder

Intervention:

Procedure: oxygen (Hyperbaric Oxygen Therapy)

http://www.clinicaltrials.gov/ct2/results?term=lyme&pg=2

NIH Clinical Center: Astute Clinician Lectures
... Lecture 1999 The Elucidation of Lyme Arthritis ... cases reported by mothers in Lyme, Connecticut. He and his colleagues ... research on the immunology of Lyme arthritis and conducted clinical trials ...
http://www.cc.nih.gov/researchers/lectures/astuteclin99.shtml- 14.0KB - NIH Clinical Center

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NIH Clinical Center: Participating in NIH Research
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The CC News is published monthly for CC employees by Clinical Center Communications.
http://www.cc.nih.gov/about/news/newsletter/1999/oct99/index.html- 45.7KB - NIH Clinical Center

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NIH Clinical Center: FY 2009 Bench-to-Bedside Proposals
... NIDCD; W. Theodore, NINDS; D. Boatman, JHU NIAID Tufts, Yale "Searching for Persistence of Infection in Lyme Disease" A. Marques, NIAID; L. Hu and S. Telford III, Tufts; P ...
http://www.cc.nih.gov/ccc/btb/awards/2009.shtml- 20.3KB - NIH Clinical Center

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31 Aug 11

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin01.shtml- 15.7KB - NIH Clinical Center

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26 Jul 11

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NIH Clinical Center: Astute Clinician Lectures
... accommodations, contact Hilda Madine,             301-594-5595      . Past Astute Clinician Lectures "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin00.shtml- 16.4KB - NIH Clinical Center

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26 Jul 11

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin02.shtml- 14.5KB - NIH Clinical Center

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26 Jul 11

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin07.shtml- 16.8KB - NIH Clinical Center

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28 Jun 11

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin05.shtml- 15.4KB - NIH Clinical Center

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28 Jun 11

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin06.shtml- 15.6KB - NIH Clinical Center

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin04.shtml- 16.5KB - NIH Clinical Center

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NIH Clinical Center: Astute Clinician Lectures
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin03.shtml- 16.6KB - NIH Clinical Center

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24 Jun 11

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NIH CC: Bench-to-Bedside Awards 2009
... NIDCD; W. Theodore, NINDS; D. Boatman, JHU NIAID Tufts, Yale "Searching for Persistence of Infection in Lyme Disease" A. Marques, NIAID; L. Hu and S. Telford III, Tufts; P ...
http://www.cc.nih.gov/ccc/btb/awards/2009.html- 43.8KB - NIH Clinical Center

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15 Jun 11

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NIH Clinical Center
... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin09.html- 17.0KB - NIH Clinical Center

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... has extensive research experience relating to many viral and immunologic conditions—including chronic fatigue syndrome, Lyme disease, HIV/AIDS, chronic hepatitis B virus, genital herpes infections, and chronic post-herpetic ...
http://www.cc.nih.gov/about/news/mfp/mfp03/bios03/straus.shtml- 14.9KB - NIH Clinical Center

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... Training Progam, DEB, NICHD Wednesday, January 12 noon-1 p.m. Bench to Bedside: Lyme Disease: Clinical Enigmas and Current Research Fred Gill, M.D., F.A.C.P., Internal ...
http://www.cc.nih.gov/about/news/grandrounds/gr00/jangr00.html- 20.8KB - NIH Clinical Center

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... committees, including the Maryland Governor's Advisory Council on AIDS, NIAID's Advisory Council for Lyme Disease and Suburban Hospital's Board of Trustees. Since coming to the NIH in ...
http://www.cc.nih.gov/about/SeniorStaff/fred_gill.html- 17.3KB - NIH Clinical Center

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02 Aug 11

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... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclinfall09.html- 17.7KB - NIH Clinical Center

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14 Jul 11

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... Congenital Adrenal Hyperplasia," December 13, 2000 - Maria I. New, M.D. "The Elucidation of Lyme Arthritis," November 3, 1999 - Brian Druker, M.D "The Link Between Teratogenesis and Carcinogenesis: Lessons ...
http://www.cc.nih.gov/researchers/lectures/astuteclin.html- 18.0KB - NIH Clinical Center

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... Brown M, Fleisher TA. Natural killer cell counts are not different between patients with post-Lyme disease syndrome and controls. Clin Vaccine Immunol. 16:1249-50, 2009. Luangwedchakarn v, Jirapongsaranuruk ...
http://www.cc.nih.gov/about/SeniorStaff/thomas_fleisher.html- 18.3KB - NIH Clinical Center

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NIH Clinical Center: Clinical Center News
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http://www.cc.nih.gov/about/news/newsletter/2005/june05/ newsletter.shtml- 59.5KB - NIH Clinical Center

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NIH Clinical Center: Infectious Diseases
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Home | Contact Us | Site Map | Search The "About the Clinical Center" navigation menu has been enchanced by javascript. You may also reach the non-javascript version from here. The "For Researchers and Physicians" ...
http://www.cc.nih.gov/about/news/newsletter/2004/oct04/ special_newsletter.shtml- 31.4KB - NIH Clinical Center

http://cc-web.cc.nih.gov:8080/query.html?charset=iso-8859-1&qt=Lyme&st=21

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